Natural killer-like T-cell lymphoma/leukemia--a case report and literature review / 中华血液学杂志
Chinese Journal of Hematology
;
(12): 226-230, 2006.
Artículo
en Chino
| WPRIM
| ID: wpr-243969
ABSTRACT
<p><b>OBJECTIVE</b>To identify the clinical and pathological features of natural killer-like T-cell lymphoma/leukemia.</p><p><b>METHODS</b>The characteristics of natural killer-like T-cell lymphoma/leukemia was discussed with report a new case and review of literatures.</p><p><b>RESULTS</b>A 16-year-old girl was referred to our hospital because of fever and disseminated cutaneous herpes and ulcer. Atypical lymphoid cells surrounded the dermal vessels with a CD3(+), CD8(+), CD4(-), CD5(-), CD10(-), CD19(-), CD57(-), CD56(+), perforin(+), granzyme B(+) immunophenotype and rearranged T-cell receptor-gamma gene implicated natural killer-like T cell origin. She was treated with prednisone and for several months. Then the patient developed progressive spleen enlargement with overt leukemia, which led to her eventual death.</p><p><b>CONCLUSIONS</b>Natural killer-like T-cell lymphoma/leukemia is a rare disease with distinctive clinical, histopathologic, and immuno phenotypic characteristics. Current treatment modalities are ineffective for most of the patients.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Células Asesinas Naturales
/
Leucemia de Células T
/
Linfoma de Células T
/
Antígeno CD56
/
Alergia e Inmunología
Tipo de estudio:
Estudio pronóstico
Límite:
Adolescente
/
Femenino
/
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Hematology
Año:
2006
Tipo del documento:
Artículo
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