The relation between overload and variability of blood pressure and overweight or obesity in patients with essential hypertension / 中华流行病学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the relationship between blood pressure variability, overweight or obesity in patients with essential hypertensive.</p><p><b>METHODS</b>A hundred ninety-one patients with essential hypertension were divided into three groups normal, overweight and obese according to body mass index (BMI). The characteristics of the variability of 24-hour ambulatory blood pressure monitoring (ABPM) in three groups were compared.</p><p><b>RESULTS</b>Blood pressure overload and variability increased parallel with the increase of BMI. In overweight group, the variabilities of systolic blood pressure at night (nSBPSD) increased 14.10%, the variabilities of diastolic blood pressure at night (nDBPSD) increased 13.15% and the variabilities of mean arterial pressure at night (nMAPSD) increased 15.92% respectively. In the obese group, the above three variabilities increased more significantly (compared to normal group P < 0.05-0.01). However, increases of the three blood pressure variabilities were observed only in the male patients.</p><p><b>CONCLUSIONS</b>The overweight or obesity increased the blood pressure overload and variabilities in patients with essential hypertension. The increases of blood pressure variabilities were observed only in male patients and at night.</p>