Discovery of two sub-types of Hantanvirus in Anhui mountain areas / 中华流行病学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the existence of hemorrhagic fever with renal syndrome (HFRS) foci in high mountains and forest areas.</p><p><b>METHODS</b>A survey was conducted in the areas of 1 400 meter altitude in Dabie mountain and of 1,600 meter altitude in Wannan mountain in the mid 1990's using methods related to epidemiology, geographic-epidemiology, serum epidemiology, pathogenic and molecular epidemiology.</p><p><b>RESULTS</b>Two strains of HFRS viruses were isolated from pulmonary tissues of Rattus niviventer and both of them were identified as A types. The analysis of the nuclei sequence showed that there were significant differences between both sub types and HTN 76-118.</p><p><b>CONCLUSION</b>It was confirmed that there were HFRS foci in the areas with 2 strains possible new sub-types of HFRS.</p>