Anaerobic culture of diabetic foot infections: organisms and antimicrobial susceptibilities
Annals of the Academy of Medicine, Singapore
; : 936-939, 2008.
Article
en En
| WPRIM
| ID: wpr-244428
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>INTRODUCTION</b>The prevalence of diabetes mellitus is high in Singapore. Infections of the lower limb are significant causes of morbidity in this population. Although the aerobic bacteriology of these infections is well-documented, there is less data available on the anaerobic pathogens involved. This study sets out to describe the anaerobic bacteria associated with diabetic foot infections, and evaluates the susceptibility to 3 antimicrobials with anaerobic activity.</p><p><b>MATERIALS AND METHODS</b>Anaerobic culture was performed on operative samples taken from diabetic foot infections. Organisms were identified through standard microbiological methods and commercial identification kits. Antimicrobial susceptibility testing to clindamycin, metronidazole and imipenem was performed by agar dilution.</p><p><b>RESULTS</b>One hundred and two strains of strict anaerobic bacteria were isolated from 30 unique specimens. The predominant anaerobic isolates were Peptostreptococcus spp. (46%) and Bacteroides fragilis group (19%). Antibiotic resistance was detected for clindamycin (18%), metronidazole (1%) and imipenem (2%).</p><p><b>CONCLUSION</b>Multiple anaerobic species can be isolated from diabetic foot infections. A significant proportion of isolates are resistant to clindamycin, while resistance to imipenem and metronidazole remains low.</p>
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Cirugía General
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Infección de la Herida Quirúrgica
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Bacterias Aerobias
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ADN Bacteriano
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Estudios Retrospectivos
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Pie Diabético
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Técnicas de Amplificación de Ácido Nucleico
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Farmacorresistencia Bacteriana Múltiple
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Usos Terapéuticos
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Quimioterapia
Tipo de estudio:
Observational_studies
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Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Annals of the Academy of Medicine, Singapore
Año:
2008
Tipo del documento:
Article