MicroRNA and left ventricular hypertrophy / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 3211-3215, 2014.
Artículo
en Chino
| WPRIM
| ID: wpr-244593
ABSTRACT
MicroRNAs (miRNA) plays an important role in biological development and disease occurrence and development, and acts as a "main switch" in biology. Among patients of essential hypertension, around 1/3 would suffer left ventricular hypertrophy (LVH). Hence, essential hypertension becomes an independent risk factor for cardiovascular diseases. And miRNAs plays an important role in the occurrence and development of LVH. This paper reviewed the role of miRNA in regulating the stress signaling pathway, defined its impact on the occurrence of LVH, and further emphasized the opportunities and challenges of miRNA as a biomarker and therapeutic target.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Transducción de Señal
/
Factores de Riesgo
/
Hipertrofia Ventricular Izquierda
/
MicroARNs
/
Hipertensión Esencial
/
Genética
/
Hipertensión
Tipo de estudio:
Estudio de etiología
/
Factores de riesgo
Límite:
Humanos
Idioma:
Chino
Revista:
China Journal of Chinese Materia Medica
Año:
2014
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS