A five-element lumped-parameter model for cerebral blood flow autoregulation / 生物医学工程学杂志
Journal of Biomedical Engineering
; (6): 1115-1123, 2009.
Article
en Zh
| WPRIM
| ID: wpr-244680
Biblioteca responsable:
WPRO
ABSTRACT
Utilizing the third-order polynomial curve fitted to the experimental data, which represents the relationship between cerebral blood flow (CBF) and mean artery blood pressure (MABP), we constructed a lumped-parameter dynamic model with 5 elements. In this model; the resistance is not constants it is determined by the fitted curve. We simulated the process of CBF autoregulation numerically by solving the govern equation of this model and got quite accurate results. Furthermore, we studied the influence of hemodynamic parameters on the CBF autoregulation by this model and proved that the characteristic resistance is the most important factor.
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Oxígeno
/
Fisiología
/
Flujo Sanguíneo Regional
/
Velocidad del Flujo Sanguíneo
/
Presión Sanguínea
/
Circulación Cerebrovascular
/
Homeostasis
/
Hipotensión
/
Metabolismo
/
Modelos Biológicos
Tipo de estudio:
Prognostic_studies
Límite:
Humans
Idioma:
Zh
Revista:
Journal of Biomedical Engineering
Año:
2009
Tipo del documento:
Article