Normalisation of urinary biomarkers to creatinine for clinical practice and research--when and why
Singapore medical journal
;
: 7-10, 2015.
Artículo
en Inglés
| WPRIM
| ID: wpr-244720
ABSTRACT
Acute kidney injury (AKI) and chronic kidney disease (CKD) are major health problems. Urinary biomarkers have both diagnostic and prognostic utility in AKI and CKD. However, how biomarker excretion rates should be reported, especially whether they should be normalised to urinary creatinine concentration (uCr), is controversial. Some studies suggest that normalisation to uCr may be inappropriate at times, as urinary creatinine excretion rate may vary greatly, depending on the situation. Notably, recent studies suggest that while normalisation of values to UCr may be valid for the evaluation of CKD and prediction of AKI sequelae and occurrences, it could be inappropriate for the diagnosis of AKI, or in the presence of certain acute kidney disease states.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Estándares de Referencia
/
Orina
/
Biomarcadores
/
Urinálisis
/
Resultado del Tratamiento
/
Creatinina
/
Insuficiencia Renal Crónica
/
Lesión Renal Aguda
/
Tasa de Filtración Glomerular
/
Riñón
Tipo de estudio:
Estudio pronóstico
Límite:
Humanos
Idioma:
Inglés
Revista:
Singapore medical journal
Año:
2015
Tipo del documento:
Artículo
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