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Clinical related factors of portal vein tumor thrombosis in patients with hepatocellular carcinoma: a logistic regression analysis / 中华外科杂志
Chinese Journal of Surgery ; (12): 733-736, 2008.
Artículo en Chino | WPRIM | ID: wpr-245541
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the related factors of portal vein tumor thrombosis (PVTT) in patients with HCC.</p><p><b>METHODS</b>A total number of 234 patients with hepatocellular carcinoma (HCC) were included in this retrospective study. Uni-variate and multi-variate logistic regression analysis were employed to analyze the association between PVTT and 18 routine clinical parameters.</p><p><b>RESULTS</b>Among the 234 patients with HCC, 15% of patients (35/235) had PVTT. Univariate logistic regression analysis revealed significant association of age (P = 0.016), gamma glutamyl transferase (GGT, P = 0.003), number of segmental invasion (P = 0.007), microvascular invasion (P < 0.01), segment location of S2 (P = 0.001), S3 (P = 0.000), S4 (P = 0.004) and S6 (P = 0.016). Multivariate analysis shows potential significant predictors of PVTT in HCC were age (RR 0.373; 95% CI 0.146-0.954; P = 0.040), the tumor location of S3 (RR 4.625; 95% CI 1.916-11. 165;P = 0.001), GGT (RR 4.091; 95% CI 1.448-11.553; P = 0.008) and microvascular invasion (RR 20.912; 95% CI 4.745-92.172; P < 0.01).</p><p><b>CONCLUSIONS</b>PVTT occurred more commonly in the younger (< 50 years old), and those with high level of GGT, segment location of S3 and microvascular invasion.</p>
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Patología / Vena Porta / Modelos Logísticos / Estudios Retrospectivos / Factores de Riesgo / Estudios de Seguimiento / Carcinoma Hepatocelular / Embolia / Neoplasias Hepáticas Tipo de estudio: Estudio de etiología / Estudio observacional / Estudio pronóstico / Factores de riesgo Límite: Adolescente / Adulto / Anciano / Aged80 / Niño / Femenino / Humanos / Masculino Idioma: Chino Revista: Chinese Journal of Surgery Año: 2008 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Patología / Vena Porta / Modelos Logísticos / Estudios Retrospectivos / Factores de Riesgo / Estudios de Seguimiento / Carcinoma Hepatocelular / Embolia / Neoplasias Hepáticas Tipo de estudio: Estudio de etiología / Estudio observacional / Estudio pronóstico / Factores de riesgo Límite: Adolescente / Adulto / Anciano / Aged80 / Niño / Femenino / Humanos / Masculino Idioma: Chino Revista: Chinese Journal of Surgery Año: 2008 Tipo del documento: Artículo