Study on correlation between aquaporin 3, 4 gene expression in gastric mucosa and severity of Pi-Wei damp-heat syndrome in patients with chronic superficial gastritis / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
; (12): 891-893, 2007.
Article
en Zh
| WPRIM
| ID: wpr-245615
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To explore the relationship between aquaporin 3,4 (AQP3, AQP4) gene expression in gastric mucosa and severity of Pi-Wei damp-heat syndrome (PWDHS) in patients with chronic superficial gastritis (CSG).</p><p><b>METHODS</b>Gastric mucosa taken from the upper part of gastric corpus was collected under gastroscope and preserved in liquid nitrogen. The gene expression of AQP3 and AQP4 was determined quantitatively by fluorescent PCR.</p><p><b>RESULTS</b>The gene expression of AQP3 and AQP4 in patients with PWDHS of moderate and severe degree was higher than that in those of mild degree and in healthy persons respectively (P <0.05 and P <0.01); and the gene expression of AQP3 in patients with PWDHS of severe degree was higher than that in those of moderate degree (P<0.05).</p><p><b>CONCLUSION</b>The gene expression of AQP3 and AQP4 in gastric mucosa was correlative with the severity of PWDHS in patients with chronic superficial gastritis, the severer the syndrome, the higher the gene expression.</p>
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Patología
/
Síndrome
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Expresión Génica
/
Enfermedad Crónica
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Reacción en Cadena de la Polimerasa de Transcriptasa Inversa
/
Diagnóstico
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Diagnóstico Diferencial
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Acuaporina 3
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Acuaporina 4
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Mucosa Gástrica
Tipo de estudio:
Diagnostic_studies
Límite:
Adult
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Female
/
Humans
/
Male
Idioma:
Zh
Revista:
Chinese Journal of Integrated Traditional and Western Medicine
Año:
2007
Tipo del documento:
Article