Effect of TCM treatment according to syndrome differentiation in enhancing curative effect and reducing side-effect of madopa / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
;
(12): 796-799, 2007.
Artículo
en Chino
| WPRIM
| ID: wpr-245640
ABSTRACT
<p><b>OBJECTIVE</b>To observe the effect of TCM treatment according to syndrome differentiation in en-hancing curative effect and reducing side-effect of madopa in patients with Parkinson' s disease (PD).</p><p><b>METHODS</b>The trial was conducted in 101 PD patients with a prospective stratified randomized and controlled method. They were assigned to group 1 in which the patients of rigidity were treated with Pabing Recipe 1 (PR1) plus Madopa tablets, group 2 with those of tremor given Pabing Recipe 3 (PR3) plus Madopa tablets, and group 3 given a fixed Chinese recipe plus Madopa tablets as the control. The treatment course for all the groups was 3 months. Clinical efficacy was evaluated with unified Parkinson's disease rating scale (UPDRS) and the adverse reactions observed before and after treatment.</p><p><b>RESULTS</b>After treatment, the 4 partial scores and the total score of UPDRS decreased significantly in group 2 (P<0.01), and the former of them and the total score declined in group 1 and 3 (P<0.01), the improvement was better in group 1 and 2 than that in group 3 (P<0.01); the improvement rate in group 1 to 3 was 95.5%, 100.0% and 83.7%, respectively, which was significantly higher in group 1 and 2 than that in group 3 (P<0.05).</p><p><b>CONCLUSION</b>TCM treatment according to syndrome differentiation could improve the clinical symptoms and reduce complications in PD patients, which could enhance curative effect and reduce side-effect of madopa.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Enfermedad de Parkinson
/
Síndrome
/
Medicamentos Herbarios Chinos
/
Dopaminérgicos
/
Benserazida
/
Levodopa
/
Estudios Prospectivos
/
Resultado del Tratamiento
/
Usos Terapéuticos
/
Diagnóstico
Tipo de estudio:
Ensayo Clínico Controlado
/
Estudio diagnóstico
/
Estudio observacional
Límite:
Anciano
/
Aged80
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Chinese Journal of Integrated Traditional and Western Medicine
Año:
2007
Tipo del documento:
Artículo
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