Bullous Pemphigoid in an Elderly Patient with Myelodysplastic Syndrome and Refractory Anemia Coupled with Excess of Blast
Annals of Dermatology
;
: S390-S392, 2011.
Artículo
en Inglés
| WPRIM
| ID: wpr-24651
ABSTRACT
Bullous pemphigoid (BP) has a recognized association with solid organ tumors, but is relatively rare in hematological malignancies. We report a 67-year-old male who developed BP after being diagnosed with myelodysplastic syndrome and refractory anemia with excess of blast (RAEB). Skin biopsy elucidated sub-epidermal bulla using direct immunofluorescence, revealing linear C3 and IgG deposits along the basement membrane. His BP was recalcitrant to the conventional treatment and only responded to a combination of high dose oral prednisolone and azathioprine. The relative refractory nature of his condition and concurrent RAEB supports a paraneoplastic nature.
Texto completo:
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Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Síndromes Paraneoplásicos
/
Piel
/
Azatioprina
/
Membrana Basal
/
Biopsia
/
Síndromes Mielodisplásicos
/
Anemia Refractaria
/
Anemia Refractaria con Exceso de Blastos
/
Inmunoglobulina G
/
Prednisolona
Límite:
Anciano
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Annals of Dermatology
Año:
2011
Tipo del documento:
Artículo
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