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Clinical Research Progress on Transformed Lymphoma -Review / 中国实验血液学杂志
Journal of Experimental Hematology ; (6): 1232-1236, 2016.
Artículo en Chino | WPRIM | ID: wpr-246785
ABSTRACT
Histologic transformation (HT) is a frequent event in the clinical course of patients with indolent lymphoma with dismal outcome. The diagnosis of HT is based on clinical manifestation, PET-CT and pathologic biopsy, and the latter is a golden standard for HT. There are contradictory data about the impact of initial management on the risk of transformation. Patients who present with HT did not receive R-CHOP or chemotherapy-naive, should receive this regimen. For the subset of patients received R-CHOP prior to HT, the second line chemotherapy for DLBCL should be adopted. Consolidation with HDT-ASCT should be considered for the suitable young patients. The radio-immunotherapy and novel drugs showed a bright perspective for the patients with HT.
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Linfoma no Hodgkin / Protocolos de Quimioterapia Combinada Antineoplásica Límite: Humanos Idioma: Chino Revista: Journal of Experimental Hematology Año: 2016 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Linfoma no Hodgkin / Protocolos de Quimioterapia Combinada Antineoplásica Límite: Humanos Idioma: Chino Revista: Journal of Experimental Hematology Año: 2016 Tipo del documento: Artículo