Evidence grading system and its usage in clinical decision-making analysis / 中华流行病学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To explore feasibility of applying evidence grading system in clinical decision-making analysis.</p><p><b>METHODS</b>Using grading system as well as a quantitative approach to generate the threshold NNT((T)), and conducting clinical decision-making analysis through one study on Asymptomatic carotid atherosclerosis.</p><p><b>RESULTS</b>NNT((T)) was 12, comparing with no-intervention in the ACA study that NNT = 6. NNT < NNT((T)) indicated the benefits of intervention outweigh the risks and costs.</p><p><b>CONCLUSION</b>To obtain the rate of adverse event and the specifying approximate cost were vital in the process of applying grading system in clinical decision-making.</p>