Distribution of rag genotypes of Porphyromonas gingivalis in patients with chronic periodontitis / 华西口腔医学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the distribution of rag genotypes of Porphyromonas gingivalis (P. gingivalis) in chronic periodontitis patients.</p><p><b>METHODS</b>Subgingival plaque samples were collected from 50 chronic periodontitis patients. The occurrence of P. gingivalis was determined by polymerase chain reaction (PCR) using 16S rDNA-specific primers. Distribution of rag genotypes was assessed in P. gingivalis positive samples by PCR.</p><p><b>RESULTS</b>The occurrence of P. gingivalis was 70.7%, and the distribution of four rag genotypes among P. gingivalis positive samples was as follows rag-1 60.4%; rag-2 23.6%; rag-3 44.3%; rag-4 15.1%, respectively.</p><p><b>CONCLUSION</b>P.gingivalis with various rag genotypes was present in subgingival plaque samples from chronic periodontitis patients, and P. gingivalis with rag-1 and rag-3 were more predominant in chronic periodontitis patients, which may be associated with the development of periodontitis.</p>