Mapping studies of type 2 diabetes mellitus gene in one family / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 123-126, 2003.
Artículo
en Chino
| WPRIM
| ID: wpr-248480
ABSTRACT
<p><b>OBJECTIVE</b>To disclose the molecular genetic mechanism of type 2 diabetes mellitus and to determine chromosomal location of type 2 diabetes mellitus gene.</p><p><b>METHODS</b>Genome-wide screening and genotyping were conducted in a family of type 2 diabetes mellitus, and linkage analysis by LINKAGE and GENEHUNTER package was used to determine the potential chromosomal location of the family of type 2 diabetes mellitus gene.</p><p><b>RESULTS</b>Evidence of linkage was found at the long arm of chromosome 2. The maximum Lod score is 1.80 and non-parameter Lod score is 5.06.</p><p><b>CONCLUSION</b>The type 2 diabetes mellitus gene of the family is located at 2q.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Linaje
/
Cromosomas Humanos Par 2
/
Genoma Humano
/
Salud de la Familia
/
Mapeo Cromosómico
/
Edad de Inicio
/
Repeticiones de Microsatélite
/
Predisposición Genética a la Enfermedad
/
Diabetes Mellitus Tipo 2
/
Genética
Límite:
Adulto
/
Anciano
/
Aged80
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Chinese Journal of Medical Genetics
Año:
2003
Tipo del documento:
Artículo
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