Progress in molecular genetics of epilepsy / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 505-507, 2002.
Artículo
en Chino
| WPRIM
| ID: wpr-248517
ABSTRACT
Epilepsy is a group of disorders characterized by recurrent seizures. The etiologies of idiopathic epilepsy commonly have a genetic basis. Gene mutations causing several of the inherited epilepsies have been mapped. In this review, the authors summarize the available information on the genetic basis of human epilepsies and epilepsy syndromes, emphasizing how genetic defects may correlate with the pathophysiological mechanisms of brain hyperexcitability and gene defects can lead to epilepsy by altering multiple and diverse aspects of neuronal function.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Investigación
/
Proyectos de Investigación
/
Canales de Potasio
/
Canales de Sodio
/
Receptores Nicotínicos
/
Canales de Potasio con Entrada de Voltaje
/
Epilepsia
/
Canal de Potasio KCNQ2
/
Subunidad beta-1 de Canal de Sodio Activado por Voltaje
/
Genética
Límite:
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Medical Genetics
Año:
2002
Tipo del documento:
Artículo
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