Researches on the polymorphism of cytochrome P450 2A6 / 中华医学遗传学杂志
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
; (6): 424-427, 2002.
Article
en Zh
| WPRIM
| ID: wpr-248531
Biblioteca responsable:
WPRO
ABSTRACT
Cytochrome P450 2A6(CYP2A6) is known as a major enzyme responsible for C-oxidation of nicotine and 7-hydroxylation of coumarin. The article reviews different alleles of CYP2A6 that have been discovered, their effect on CYP 2A6 activity and the relationship between genetic polymorphism of CYP2A6 and smoking behavior as well as susceptibility of lung and esophageal cancer in different individuals.
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Polimorfismo Genético
/
Investigación
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Neoplasias Esofágicas
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Hidrocarburo de Aril Hidroxilasas
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Fumar
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Predisposición Genética a la Enfermedad
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Citocromo P-450 CYP2A6
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Genética
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Oxigenasas de Función Mixta
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Neoplasias Pulmonares
Límite:
Humans
Idioma:
Zh
Revista:
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
Año:
2002
Tipo del documento:
Article