The function of protein kinase C in myocardial fibrosis / 药学学报
Acta Pharmaceutica Sinica
; (12): 1467-1471, 2010.
Article
en Zh
| WPRIM
| ID: wpr-250608
Biblioteca responsable:
WPRO
ABSTRACT
Myocardial fibrosis is the common results of the development of a variety of heart diseases which leads to extracellular matrix protein metabolic disorders and causes cardiac remodeling owing to cardiac fibroblasts proliferation, eventually results in malignant arrhythmia, heart failure, and even the occurrence of sudden cardiac death. Effective inhibition of myocardial remodeling could prevent the occurrence of sudden death. To know the protein kinase C (PKC) effective mechanism of regulation on myocardial fibrosis, a new therapeutic target for reversing myocardial remodeling might be provided.
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Patología
/
Farmacología
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Fibrosis
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Proteína Quinasa C
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Clasificación
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Cardiomegalia
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Remodelación Ventricular
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Metaloproteinasa 9 de la Matriz
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Indoles
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Maleimidas
Límite:
Animals
/
Humans
Idioma:
Zh
Revista:
Acta Pharmaceutica Sinica
Año:
2010
Tipo del documento:
Article