The crystalline polymorph control and selection of gabapentin with polymer heteronuclei / 药学学报
Acta Pharmaceutica Sinica
;
(12): 109-113, 2010.
Artículo
en Chino
| WPRIM
| ID: wpr-250611
ABSTRACT
The pharmaceutical properties, including the physical and chemical properties, and the bioavailability are greatly influenced by their polymorphism. In this paper the polymer heteronuclei were used to produce the gabapentin polymorphs that were characterized by X-ray powder diffraction, FT-IR and DSC. The results indicated that the polymer heteronuclei are an effective method to control and select the gabapentin polymorphism. One new polymorph of gabapentin was found besides all known gabapentin polymorphs.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Polímeros
/
Difracción de Rayos X
/
Rastreo Diferencial de Calorimetría
/
Estructura Molecular
/
Química
/
Espectroscopía Infrarroja por Transformada de Fourier
/
Cristalización
/
Ácidos Ciclohexanocarboxílicos
/
Ácido gamma-Aminobutírico
/
Aminas
Idioma:
Chino
Revista:
Acta Pharmaceutica Sinica
Año:
2010
Tipo del documento:
Artículo
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