Percutaneous permeability study for patches Shangshi Zhitong on different kinds of bases / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 2960-2962, 2011.
Artículo
en Chino
| WPRIM
| ID: wpr-251249
ABSTRACT
<p><b>OBJECTIVE</b>To study the percutaneous permeability of patches Shangshi Zhitong on different kinds of bases with the permeation percentage of brucine, strychnine and atropine.</p><p><b>METHOD</b>Using modified Franz difusion to investigate the penetration quantity of brucine, strychnine and atropine. The contents of brucine, strychnine and atropine were determined by HPLC.</p><p><b>RESULT</b>The average accumulative permeation percentage of brucine, strychnine and atropine on new base were 53.25%, 74.52% were 34.32%, respectively, and on old base are 54.90%, 50.24%, 46. 54%, respectively.</p><p><b>CONCLUSION</b>The new base benefits the lipophilic drugs and releases more stably.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Permeabilidad
/
Piel
/
Medicamentos Herbarios Chinos
/
Farmacocinética
/
Ratas Sprague-Dawley
/
Metabolismo
Límite:
Animales
Idioma:
Chino
Revista:
China Journal of Chinese Materia Medica
Año:
2011
Tipo del documento:
Artículo
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