A Case of Florid Cutaneous Papillomatosis and Tripe Palm / 대한피부과학회지

ABSTRACT

Florid cutaneous papillomatosis(FCP) is a disease consisting of multiple acuminate keratotic papules in association with an underlying malignancy. Most common underlying malignancy is gastric adenocarcinoma. Other associated malignancies are breast cancer, bladder cancer, hepatobiliary cancer, ovarian cancer and uterine cancer. An association of FCP with other signs of internal cancer is common, with malignant acanthosis nigricans usually appearing many times with sign of Leser-Trelat. We experienced a florid cutaneous papillomatosis associated gastric adenocarcinoma in an 84 years old woman. The patient had a severe itching and showed numerous tiny papules on the trunk(FCP) and brown verrucose papules on the axillae(acanthosis nigricans) and hyperkeratotic yellowish tiny papules on the palms(tripe palm). Histopathologically, the lesion of the trunk exhibited papillomatosis, hyperkeratosis, and acanthosis in the epidermis. Gastroscopic biopsy revealed gastric adenocarcinoma.