Twelve benzene derivatives from Clausena excavata / 药学学报
Acta Pharmaceutica Sinica
;
(12): 1689-1693, 2014.
Artículo
en Inglés
| WPRIM
| ID: wpr-251835
ABSTRACT
A new phenethanol, (2'R)-4-(2', 3'-dihydroxy-3'-methyl-butanoxy)-phenethanol (1), along with other eleven known benzene derivatives (2-12) were isolated from the roots, stems and leaves of Clausena excavata (Rutaceae). Compounds 3 and 4 are new natural products, and compounds 5-8, 10-12 were isolated from C. excavata for the first time. Their structures were elucidated on the basis of MS, 1D and 2D NMR spectroscopic analyses including HSQC, COSY and HMBC experiments. 1 was tested for its cytotoxicities against A549, HeLa and BGC-823 cancer cell lines, and antimicrobial activities against Candida albicans and Staphylococcus aureus. The results showed that 1 did not exhibit cytotoxic and antimicrobial activities.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Staphylococcus aureus
/
Derivados del Benceno
/
Candida albicans
/
Células HeLa
/
Espectroscopía de Resonancia Magnética
/
Estructura Molecular
/
Química
/
Tallos de la Planta
/
Raíces de Plantas
/
Hojas de la Planta
Límite:
Humanos
Idioma:
Inglés
Revista:
Acta Pharmaceutica Sinica
Año:
2014
Tipo del documento:
Artículo
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