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Twelve benzene derivatives from Clausena excavata / 药学学报
Acta Pharmaceutica Sinica ; (12): 1689-1693, 2014.
Artículo en Inglés | WPRIM | ID: wpr-251835
ABSTRACT
A new phenethanol, (2'R)-4-(2', 3'-dihydroxy-3'-methyl-butanoxy)-phenethanol (1), along with other eleven known benzene derivatives (2-12) were isolated from the roots, stems and leaves of Clausena excavata (Rutaceae). Compounds 3 and 4 are new natural products, and compounds 5-8, 10-12 were isolated from C. excavata for the first time. Their structures were elucidated on the basis of MS, 1D and 2D NMR spectroscopic analyses including HSQC, COSY and HMBC experiments. 1 was tested for its cytotoxicities against A549, HeLa and BGC-823 cancer cell lines, and antimicrobial activities against Candida albicans and Staphylococcus aureus. The results showed that 1 did not exhibit cytotoxic and antimicrobial activities.
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Staphylococcus aureus / Derivados del Benceno / Candida albicans / Células HeLa / Espectroscopía de Resonancia Magnética / Estructura Molecular / Química / Tallos de la Planta / Raíces de Plantas / Hojas de la Planta Límite: Humanos Idioma: Inglés Revista: Acta Pharmaceutica Sinica Año: 2014 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Staphylococcus aureus / Derivados del Benceno / Candida albicans / Células HeLa / Espectroscopía de Resonancia Magnética / Estructura Molecular / Química / Tallos de la Planta / Raíces de Plantas / Hojas de la Planta Límite: Humanos Idioma: Inglés Revista: Acta Pharmaceutica Sinica Año: 2014 Tipo del documento: Artículo