Whole-genome sequencing: a new approach for understanding of pathogenesis and individualized treatment of cancer / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 103-108, 2013.
Artículo
en Chino
| WPRIM
| ID: wpr-252657
ABSTRACT
With the development of sequencing technology, the cost of whole-genome sequencing was significantly declined.Meanwhile, with the application of combined whole-genome sequencing with epigenetic analysis on methylation and histone acetylation, the comprehensive and systematic analysis of numerous samples became a reality and we are able to re-understand the genesis and development of cancer. New ideas are emerging in comparative genomics research methods, from comparison of genomes among different individuals to horizontal self-comparison of different tissues and vertical self-comparison of genomes recently.Individualized diagnosis and treatment of cancer has shown a bright future.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Terapéutica
/
Genoma Humano
/
Análisis de Secuencia de ADN
/
Medicina de Precisión
/
Genética
/
Métodos
/
Neoplasias
Tipo de estudio:
Estudio de etiología
Límite:
Humanos
Idioma:
Chino
Revista:
Journal of Zhejiang University. Medical sciences
Año:
2013
Tipo del documento:
Artículo
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