Study on visual evoked related potentials in young adults of different COMT genotypes by using a numeric working memory task / 中国应用生理学杂志
Chinese Journal of Applied Physiology
;
(6): 479-482, 2008.
Artículo
en Chino
| WPRIM
| ID: wpr-252735
ABSTRACT
<p><b>AIM</b>To explore the change of number working memory ability in healthy young adults, a continuous 3-back number working memory task were performed for an hour and 12 Blocks according to different COMT genotypes of young adults.</p><p><b>METHODS</b>18 different genotype subjects were chosen from 112 healthy young adults, P3 event-related potentials was utilized to observe the relationship between this COMT polymorphism and cortical physiology in a continuous working memory task.</p><p><b>RESULTS</b>Subjects bearing the Val/Val homozygote had significantly higher mean P3 amplitudes than Val/Met heterozygote (P < 0.01), however, no significant differences in comparison to Met/Met homozygote.</p><p><b>CONCLUSION</b>Val/Met Heterozygote subjects are associated with the poorest performance of working memory. There is a relationship between COMT genotype and P3 visual event-related potentials evoked from 3-back task.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fisiología
/
Polimorfismo Genético
/
Encéfalo
/
Catecol O-Metiltransferasa
/
Potenciales Relacionados con Evento P300
/
Potenciales Evocados Visuales
/
Genética
/
Genotipo
/
Memoria a Corto Plazo
Límite:
Adulto
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Chinese Journal of Applied Physiology
Año:
2008
Tipo del documento:
Artículo
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