Inhibition of glucoraphenin enzymolysis in Raphani Semen by processing / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To explore material basis of the pharmacological differences between the roasting and pro-roasting Raphani Semen.</p><p><b>METHOD</b>The two new sulfur-containing compounds (A209 and B221) were found changed after processing in the water decoction. The common precursor-C3 of A209 and B211 and the precursor of C3 were seperated and purified. Their transforming relationship was proved.</p><p><b>RESULT</b>The result showed that glucosinolates could decompose into sulforaphane and transform into A209 and B221 further in the boiling process.</p><p><b>CONCLUSION</b>This study provides some experimental evidences for revealing the mechanism of Raphani Semen processing.</p>