Research progress in molecular biology of pediatric myelodysplastic syndrome / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 957-961, 2014.
Artículo
en Chino
| WPRIM
| ID: wpr-254158
ABSTRACT
Marked differences have been found in molecular characteristics between pediatric and adult myelodysplastic syndrome (MDS) patients. The incidence of gene mutations associated with myeloid malignances in pediatric patients is lower than in adults, while the incidence of aberrant methylation is similar between them. It is also worth noting that novel molecular factors such as mitochondrial DNA mutations may play a role in the pathogenesis of childhood MDS. This article summarizes research advances in molecular biology of pediatric MDS.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Síndromes Mielodisplásicos
/
ADN Mitocondrial
/
Metilación de ADN
/
Genética
/
Mutación
Límite:
Niño
/
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Contemporary Pediatrics
Año:
2014
Tipo del documento:
Artículo
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