Your browser doesn't support javascript.
loading
Therapeutic effect of acupuncture treatment on ischemic hypoxic neonate rats with cerebral palsy / 中国应用生理学杂志
Chinese Journal of Applied Physiology ; (6): 473-476, 2015.
Artículo en Chino | WPRIM | ID: wpr-254986
ABSTRACT
<p><b>OBJECTIVE</b>To explore the mechanisms of acupuncture treatment promoting the motor function recovery of neonate rats with cerebral palsy.</p><p><b>METHODS</b>The improved hypoxic-ischemic encephalopathy (HIE) means was performed to establish the model of neonate rats with cerebral palsy. All neonate rats were randomly divided into 3 groups sham group, model group and acupuncture group (n = 20). We observed and scored motor function of rats, measured the levels of superoxide dismutase (SOD) and malondialdehyde (MDA) in serum, and also measured the expression of synaptophysin (SYP) and growth associated protein-43 (GAP-43) in the diseased region of cerebral tissue.</p><p><b>RESULTS</b>The motor function scores (11.3 +/- 0.29) and the serum level of SOD (147.1 +/- 12.7) U/ml in acupuncture treatment group were higher than those of model group ( P < 0.05). The serum level of MDA was lower in acupuncture treatment group than that of model group (P < 0.05). The expression of SYP and GAP-43 in the diseased region of cerebral tissue of acupuncture treatment group were higher than those of model group ( P < 0.05) .</p><p><b>CONCLUSION</b>Acupuncture-therapy could improve the motor function of neonate rats with cerebral palsy by decreasing the content of MDA in serum, increasing the contents of SOD in serum, and prolonging the upregulation of SYP and GAP-43 expressions in hmin tissue.</p>
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Superóxido Dismutasa / Terapéutica / Terapia por Acupuntura / Parálisis Cerebral / Sinaptofisina / Proteína GAP-43 / Hipoxia-Isquemia Encefálica / Modelos Animales de Enfermedad / Animales Recién Nacidos / Malondialdehído Tipo de estudio: Estudio pronóstico Límite: Animales Idioma: Chino Revista: Chinese Journal of Applied Physiology Año: 2015 Tipo del documento: Artículo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Superóxido Dismutasa / Terapéutica / Terapia por Acupuntura / Parálisis Cerebral / Sinaptofisina / Proteína GAP-43 / Hipoxia-Isquemia Encefálica / Modelos Animales de Enfermedad / Animales Recién Nacidos / Malondialdehído Tipo de estudio: Estudio pronóstico Límite: Animales Idioma: Chino Revista: Chinese Journal of Applied Physiology Año: 2015 Tipo del documento: Artículo