Epidemiology, diagnosis and treatment of Middle East respiratory syndrome / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
; (6): 443-450, 2015.
Article
en Zh
| WPRIM
| ID: wpr-255171
Biblioteca responsable:
WPRO
ABSTRACT
Middle East respiratory syndrome (MERS) has raised global public health concerns. The recent outbreak of MERS coronavirus (MERS-CoV) infection has led to 1 338 laboratory-confirmed cases in 26 countries worldwide as reported till 19 June, 2015. MERS-CoV may be considered a zoonotic virus that has crossed the species barrier to humans, but the pathogenesis and the routes of transmission are not completely understood. Most MERS-CoV cases reported thus far have a history of residence in or travel to the Middle East. Human-to-human transmission though was observed on some occasions in Korea, it is documented as non-sustainable event. The envelope spike glycoprotein on the surface of MERS-CoV which mediates receptor binding, membrane fusion and viral entry is thought to be involved in the mechanism of MERS-CoV.No specific and effective treatment for MERS-CoV is currently recommended, although supportive treatment has played an important role. Prophylactic strategies are necessary to prevent MERS-CoV infection.
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Fisiología
/
Terapéutica
/
Virulencia
/
Epidemiología
/
Infecciones por Coronavirus
/
Diagnóstico
/
Internalización del Virus
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Glicoproteína de la Espiga del Coronavirus
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Coronavirus del Síndrome Respiratorio de Oriente Medio
/
Metabolismo
Tipo de estudio:
Diagnostic_studies
/
Screening_studies
Límite:
Humans
Idioma:
Zh
Revista:
Journal of Zhejiang University. Medical sciences
Año:
2015
Tipo del documento:
Article