Clinical Response of 277 Patients with Spinal Cord Injury to Stem Cell Therapy in Iraq
International Journal of Stem Cells
;
: 76-78, 2012.
Artículo
en Inglés
| WPRIM
| ID: wpr-25519
ABSTRACT
BACKGROUND AND OBJECTIVES:
Spinal cord injury is a common neurological problem secondary to car accidents, war injuries and other causes, it may lead to varying degrees of neurological disablement, and apart from physiotherapy there is no available treatment to regain neurological function loss. Our aim is to find a new method using autologous hematopoietic stem cells to gain some of the neurologic functions lost after spinal cord injury. METHODS ANDRESULTS:
277 patients suffering from spinal cord injury were submitted to an intrathecally treatment with peripheral stem cells. The cells were harvested from the peripheral blood after a treatment with G-CSF and then concentrated to 4~6 ml. 43% of the patients improved; ASIA score shifted from A to B in 88 and from A to C in 32. The best results were achieved in patients treated within one year from the injury.CONCLUSIONS:
Since mesenchymal cells increase in the peripheral blood after G-CSF stimulation, a peripheral blood harvest seems easier and cheaper than mesenchymal cell cultivation prior to injection. It seems reasonable treatment for spinal cord injury.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Asia
/
Médula Espinal
/
Traumatismos de la Médula Espinal
/
Células Madre
/
Estrés Psicológico
/
Células Madre Hematopoyéticas
/
Factor Estimulante de Colonias de Granulocitos
/
Irak
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
International Journal of Stem Cells
Año:
2012
Tipo del documento:
Artículo
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