Progress on matrix metalloproteinase in axonal regeneration / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 95-100, 2015.
Artículo
en Chino
| WPRIM
| ID: wpr-255227
ABSTRACT
Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases. MMPs can degrade and remodel extracellular matrix, also active or inactive many molecules attaching to matrix including receptors, growth factors and cytokines, so that injury-induced MMPs can change the extracellular environment to affect the axonal regeneration in central nervous system. In this review, with spinal cord injury (SCI) as an example we discuss the effects of MMPs on inflammation, neuronal viability, extracellular molecules, glial scar and axonal remyelination, which are all important to axonal regeneration.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Traumatismos de la Médula Espinal
/
Axones
/
Neuroglía
/
Cicatriz
/
Metaloproteinasas de la Matriz
/
Matriz Extracelular
/
Regeneración Nerviosa
Idioma:
Chino
Revista:
Journal of Zhejiang University. Medical sciences
Año:
2015
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS