Cancer Stem Cells in Brain Tumors and Their Lineage Hierarchy
International Journal of Stem Cells
; : 12-15, 2012.
Article
en En
| WPRIM
| ID: wpr-25527
Biblioteca responsable:
WPRO
ABSTRACT
Despite recent advances in the development of novel targeted chemotherapies, the prognosis of malignant glioma remains dismal. The chemo-resistance of this tumor is attributed to tumor heterogeneity. To explain this unique chemo- resistance, the concept of cancer stem cells has been evoked. Cancer stem cells, a subpopulation of whole tumor cells, are now regarded as candidate therapeutic targets. Here, the author reviews and discusses the cancer stem cell concept.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Pronóstico
/
Células Madre Neoplásicas
/
Características de la Población
/
Encéfalo
/
Neoplasias Encefálicas
/
Glioma
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
International Journal of Stem Cells
Año:
2012
Tipo del documento:
Article