Effect of Spatholobus suberectus on the bone marrow cells and related cytokines of mice / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 352-355, 2004.
Artículo
en Chino
| WPRIM
| ID: wpr-256355
ABSTRACT
<p><b>OBJECTIVE</b>To study the effect of Spatholobus suberectus on proliferation and the hematonic mechanism.</p><p><b>METHOD</b>The techniques of culture of hematopoietic cell and hematopoietic growth factor (HGF) assay were used.</p><p><b>RESULT</b>Spatholobus suberectus could obviously promote the proliferation of bone marrow cells in healthy and anaemic mice. The culture media of spleen cell, macrophage, lung and skeletal muscle treated with S. suberectus had much stronger stimulating effects on hematopoietic cells.</p><p><b>CONCLUSION</b>S. suberectus may enhance hematopoiesis by directly or indirectly stimulating stroma cell in hematopoietic inductive microenvironment and muscle tissue to secrete some HGF (Epo, GM-CSF, IL, and MK-CSF). This is one of the biological mechanisms for hematonic effect of S. suberectus.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Farmacología
/
Plantas Medicinales
/
Células de la Médula Ósea
/
Medicamentos Herbarios Chinos
/
Química
/
Factores Estimulantes de Colonias
/
Tallos de la Planta
/
Biología Celular
/
Proliferación Celular
Límite:
Animales
Idioma:
Chino
Revista:
China Journal of Chinese Materia Medica
Año:
2004
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS