Diversity of intestinal microflora in patients with depression after stroke / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the changes in the population and distribution intestinal microflora and their relationship with depression in post-stroke patients.</p><p><b>METHODS</b>Fecal specimens were obtained from 32 patients with post-stroke depression and 30 healthy adults for gene sequencing of 16S RNA V3 region of the intestinal microorganism using Roche/45 high-throughput sequencing platform.</p><p><b>RESULTS</b>The genus and species of intestinal bacteria showed significant differences between the post-stroke patients and health adults.</p><p><b>CONCLUSION</b>Significant changes in the structure of intestinal flora occur in patients with post-stroke depression.</p>