Application of TRUST, TP-ELISA and TPPA in the serologic diagnosis of syphilis / 中华男科学杂志
National Journal of Andrology
;
(12): 1020-1022, 2012.
Artículo
en Chino
| WPRIM
| ID: wpr-256998
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the application value of toluidine red unheated serum test (TRUST), treponema pallidum enzyme-linked immunosorbent assay (TP-ELISA) and treponema pallidum particle agglutination assay (TPPA) in the serologic diagnosis of syphilis.</p><p><b>METHODS</b>We collected serum samples from 12 622 inpatients, 2 253 outpatients and 1 500 subjects in the medical examination center, and screened them by TRUST and TP-ELISA, followed by quantitative tests using TRUST and TPPA.</p><p><b>RESULTS</b>Among the 16 375 cases, clinically diagnosed syphilis was confirmed in 384, with a positive rate of 100% either by TRUST (12 -116) or TPPA (180 - 12 560), and 92.2% by TP-ELISA.</p><p><b>CONCLUSION</b>TP-ELISA and TRUST should be simultaneously used for syphilis screening, but not TP-ELISA alone, and the results should be confirmed by TPPA. The combination of the three methods plays a valuable role in reducing the misdiagnosis and missed diagnosis, and contributes to the early and accurate diagnosis of syphilis.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Treponema pallidum
/
Sangre
/
Ensayo de Inmunoadsorción Enzimática
/
Serodiagnóstico de la Sífilis
/
Sífilis
/
Diagnóstico
/
Métodos
Tipo de estudio:
Estudio diagnóstico
Límite:
Adolescente
/
Adulto
/
Anciano
/
Aged80
/
Niño
/
Child, preschool
/
Humanos
/
Lactante
/
Recién Nacido
Idioma:
Chino
Revista:
National Journal of Andrology
Año:
2012
Tipo del documento:
Artículo
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