Evaluation of Off-label Use of Oral Glucocorticoids in Outpatients / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 430-434, 2015.
Artículo
en Chino
| WPRIM
| ID: wpr-257616
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the off-label use of oral glucocorticoids in outpatients.</p><p><b>METHODS</b>The information of outpatient glucocorticoids prescriptions from January 1st to June 30th in 2012 were collected from the information system in our hospital, then the software of Excel was employed to statistically analyze the data including the amount of drugs used in different departments,as well as the age, sex, and diagnosis of the patients. The diagnoses were compared with those included in the labels approved by China Food and Drug Administration and US Food and Drug Administration and domestic and foreign guidelines.</p><p><b>RESULTS</b>It was found that 16.53% of the cases were off-label use,and dexamethasone had the highest proportion (60.50%) of off-label use. Most of the off-label use had evidence support, such as multiple myeloma and myasthenia gravis, while some cases did not, such as epilepsy and sudden deafness.</p><p><b>CONCLUSION</b>The management of off-label use should be further strengthened to promote the safe and rational use of glucocorticoids.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pacientes Ambulatorios
/
China
/
Administración Oral
/
Epilepsia
/
Uso Fuera de lo Indicado
/
Glucocorticoides
Tipo de estudio:
Guía de Práctica Clínica
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Chino
Revista:
Acta Academiae Medicinae Sinicae
Año:
2015
Tipo del documento:
Artículo
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