Exploring the three-dimensional structure of dermal tissues of normal skin and scar in rat with synchrotron radiation X-ray imaging technology / 中华烧伤杂志
Chinese Journal of Burns
;
(6): 5-8, 2012.
Artículo
en Chino
| WPRIM
| ID: wpr-257824
ABSTRACT
<p><b>OBJECTIVE</b>To compare the morphological difference between dermal tissue of normal skin and that of scar in rat, and to explore its structural pattern.</p><p><b>METHODS</b>The full-thickness skin and the scar tissue formed 3 weeks after wound healing from SD rats were harvested as samples, which were prepared appropriately afterwards. Samples were scanned and imaged with synchrotron radiation technology, micro-CT, and phase-contrast imaging technology. The images were rebuilt with three-dimensional software.</p><p><b>RESULTS</b>The micro-CT was materialized by using X-ray generated by synchrotron radiation light source. The structure of dermal tissues was clearly shown with the assistance of phase-contrast imaging technology in the process. It was demonstrated that the dermal tissues of normal skin of rat were mainly composed of collagenous fibers, which twined together to form an olive-like structure. These olive-like structures as basic units were arranged randomly in a certain way. The collagenous fibers in dermal tissue of the scar were arranged in a parallel manner, while some fibers were crooked and arranged in a disorderly manner.</p><p><b>CONCLUSIONS</b>Dermal tissue of normal skin in rat has stable three-dimensional structure, and its basic structure and manner of composition are obviously different from those of scar dermal tissue.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Piel
/
Cicatrización de Heridas
/
Diagnóstico por Imagen
/
Tomografía Computarizada por Rayos X
/
Microscopía de Contraste de Fase
/
Cicatriz
/
Sincrotrones
/
Ratas Sprague-Dawley
/
Dermis
Tipo de estudio:
Estudio diagnóstico
Límite:
Animales
Idioma:
Chino
Revista:
Chinese Journal of Burns
Año:
2012
Tipo del documento:
Artículo
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