In vivo proton magnetic resonance spectroscopy of hepatocellular carcinoma and cholangiocarcinoma / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 151-154, 2009.
Artículo
en Chino
| WPRIM
| ID: wpr-259053
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the value of in vivo proton magnetic resonance spectroscopy (1H MRS) in the assessment of hepatocellular carcinoma (HCC) and cholangiocarcinoma.</p><p><b>METHODS</b>1H MRS was performed in normal volunteers and in patients with pathologically confirmed HCC and cholangiocarcinomas using a whole-body 1.5-T scanner. The choline-to-lipid ratios were measured by dividing the peak area of choline at 3.2 ppm and lipid at 1.3 ppm.</p><p><b>RESULTS</b>The ratio of choline-to-lipid for normal liver, cholangiocarcinomas, and HCC were 0.07 +/- 0.04, 0.11 +/- 0.06, and 0.52 +/- 0.15, respectively. The ratio of choline-to-lipid was significantly higher in HCC compared than those in cholangiocarcinomas or normal livers (P < 0.05). However, it was not significantly different between cholangiocarcinomas and normal livers (P > 0.05).</p><p><b>CONCLUSION</b>In vivo 1H MRS can reflect the pathological changes of HCC and cholangiocarcinomas at metabolic level and thus is useful in the diagnosis of these two cancers.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Protones
/
Neoplasias de los Conductos Biliares
/
Conductos Biliares Intrahepáticos
/
Imagen por Resonancia Magnética
/
Espectroscopía de Resonancia Magnética
/
Estudios de Casos y Controles
/
Estudios Retrospectivos
/
Colangiocarcinoma
/
Carcinoma Hepatocelular
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
Límite:
Adulto
/
Anciano
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Acta Academiae Medicinae Sinicae
Año:
2009
Tipo del documento:
Artículo
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