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Relationship of polymorphism of SG13S114A/T in ALOX5AP gene with atherosclerotic cerebral infarction / 浙江大学学报·医学版
Article en Zh | WPRIM | ID: wpr-259255
Biblioteca responsable: WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the relationship of the polymorphism of SG13S114A/T in ALOX5AP gene with atherosclerotic cerebral infarction (ACI).</p><p><b>METHODS</b>By polymerase chain reaction and restriction fragment length polymorphism, polymorphism of SG13S114A/T in ALOX5AP gene in 412 cases with ACI and 368 non-ACI controls were analyzed.</p><p><b>RESULT</b>There were no statistically significant differences in the ALOX5AP gene SG13S114 AA genotype and A allele frequencies between ACI group and control group (P>0.05).</p><p><b>CONCLUSION</b>The results do not support genotype SG13S114 A allele as the risk gene for ACI.control group.</p>
Asunto(s)
Texto completo: 1 Índice: WPRIM Asunto principal: Polimorfismo de Longitud del Fragmento de Restricción / Arteriosclerosis Intracraneal / Infarto Cerebral / Alelos / Proteínas Activadoras de la 5-Lipooxigenasa / Genética / Genotipo Límite: Female / Humans / Male Idioma: Zh Revista: Zhejiang Daxue xuebao. Yixue ban Año: 2009 Tipo del documento: Article
Texto completo: 1 Índice: WPRIM Asunto principal: Polimorfismo de Longitud del Fragmento de Restricción / Arteriosclerosis Intracraneal / Infarto Cerebral / Alelos / Proteínas Activadoras de la 5-Lipooxigenasa / Genética / Genotipo Límite: Female / Humans / Male Idioma: Zh Revista: Zhejiang Daxue xuebao. Yixue ban Año: 2009 Tipo del documento: Article