Investigation on therapeutic effect and mechanism of acupuncture at Fengchi (GB 20) and "Gongxue" for treatment of patients with vertebral-basilar insufficiency / 中国针灸

ABSTRACT

<p><b>OBJECTIVE</b>To compare the difference of the therapeutic effect of acupuncture and western medicine on the patients with vertebral-basilar insufficiency (VBI), and investigate its mechanism.</p><p><b>METHODS</b>According to the different velocity of blood flow recorded by Transcranial Doppler (TCD), sixty patients with VBI were divided into an acupunture group (31 cases) and a western medicine group (29 cases). In the acupuncture group, the patients were punctured at Fengchi (GB 20) and "Gongxue" (Extra). In the western medicine group, the patients were orally given the Flunarizine hydrochlorid capsules. Before and after two-week treatment, the clinical symptoms and related data of TCD were compared, analyzed and evaluated.</p><p><b>RESULTS</b>The clinical symptoms were obviously improved in the acupuncture group, which was better than the western medicine group (P < 0.05). Acupuncture not only could up-regulate the velocity of vertebral-basilar blood flow (VBF) on the patients with slower VBF of peak-systolic phase (Vs), end-diastolic phase (Vd) and mean value (Vm), but also reduced the VBF on the patients with faster Vs, Vd and Vm. In comparison of the data before and after treatment, there were significantly differences in two groups (P < 0.05), however, there were no difference between the two groups (all P > 0.05). On the index of vascular pulsation (PI), resistance index (RI) and Vs/Vd, there were no difference in both groups before and after treatment (all P > 0.05).</p><p><b>CONCLUSION</b>Acupuncturing at Fengchi (GB 20) and "Gongxue" has bidirectional and beneficial function of regulation on the VBF, but no active role on the compatibility of vertebral-basilar blood vessel.</p>