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The efficacy of artificial liver support system treatment on hepatic failure in China: a meta-analysis / 中华肝脏病杂志
Chinese Journal of Hepatology ; (12): 732-734, 2006.
Artículo en Chino | WPRIM | ID: wpr-260613
ABSTRACT
<p><b>OBJECTIVE</b>Conducting a meta-analysis to evaluate the efficacy of artificial liver support system (ALSS) in the treatment of hepatic failure in China.</p><p><b>METHODS</b>Clinical trials comparing ALSS vs. routine medical treatment of hepatic failure in China were identified from computer-based literature. The pooled odds ratio and 95% confidence interval (CI) of prognostic indicators, such as survival rate and clinical improvement rate at discharge, were used to measure the magnitude of the efficacy.</p><p><b>RESULTS</b>Ten trials including 1030 patients were identified. The odds ratio (95% CI) of survivorship or improvement of ALSS over routine medical treatment in early, intermediate and advanced stages of hepatic failure were 3.72 (2.03-6.83), 2.79 (2.88-4.14) and 1.85 (0.96-3.56) respectively.</p><p><b>CONCLUSION</b>ALSS treatment is more effective in early and intermediate stages of hepatic failure than routine medical treatment, but not in its advanced stage.</p>
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Pronóstico / Terapéutica / Resultado del Tratamiento / Fallo Hepático / Hígado Artificial Tipo de estudio: Estudio pronóstico / Revisiones Sistemáticas Evaluadas Límite: Humanos Idioma: Chino Revista: Chinese Journal of Hepatology Año: 2006 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Pronóstico / Terapéutica / Resultado del Tratamiento / Fallo Hepático / Hígado Artificial Tipo de estudio: Estudio pronóstico / Revisiones Sistemáticas Evaluadas Límite: Humanos Idioma: Chino Revista: Chinese Journal of Hepatology Año: 2006 Tipo del documento: Artículo