Chemical constituents and bioactivity of Kalimeris indica / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 3172-3174, 2010.
Article
en Zh
| WPRIM
| ID: wpr-260728
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the constituents of Kalimeris indica and its bioactivity.</p><p><b>METHOD</b>The constituents were isolated by various chromatographic techniques and their structures were elucidated by their physicochemical properties and the spectral data analysis. Use the disk diffusion method, see whether a sample can produce inhibition zone and its round size, semi-quantitatively evaluate the samples antimicrobial activity.</p><p><b>RESULT</b>Eight compounds were isolated and identified as succinic acid (1), glycerolmonopalmitate (2), protocatechuic acid (3), uracil (4), syringic acid (5), protocatechuic acid methyl ester (6), esculetin (7), medicagenic acid (8). The result of activity screening indicate that succinic and syringic acid have bacteriostasis to bacillus subtilis.</p><p><b>CONCLUSION</b>All Compounds were isolated from the genus Kalimeris for the first time, succinic acid (1) and syringic acid (5) have bacteriostasis to bacillus subtilis.</p>
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Índice:
WPRIM
Asunto principal:
Farmacología
/
Bacterias
/
Extractos Vegetales
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Química
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Asteraceae
/
Antibacterianos
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Año:
2010
Tipo del documento:
Article