Research on preparation and quality control of drug-carried poly lactic-co-glycolic acid microbubble / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 1051-1055, 2010.
Artículo
en Chino
| WPRIM
| ID: wpr-260940
ABSTRACT
This research was aimed to develop the technique and formula for the preparation of stable and effective microbubbles containing hydrophilic drugs. We prepared EB-PLGA microbubbles and evaluated its drug loading and burst release to choose the best technique and formula. The result of optimizing formula was W1/O (115), EB-PLGA (0.04), PVA (5%). The burst release decreased after the addition of supplemental agent and the change of method for preparation. We concluded that the optimizing formula could elevate drug loading and decrease burst release obviously.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Ácido Poliglicólico
/
Control de Calidad
/
Portadores de Fármacos
/
Química
/
Ácido Láctico
/
Microburbujas
Idioma:
Chino
Revista:
Journal of Biomedical Engineering
Año:
2010
Tipo del documento:
Artículo
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