Effect of herbs in early intervention of children with Henoch-Schonlein purpura nephritis / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
;
(12): 504-507, 2011.
Artículo
en Chino
| WPRIM
| ID: wpr-260953
ABSTRACT
<p><b>OBJECTIVE</b>To observe the effect of blood activating and cooling, stasis removing herbs on the occurrence rate of Henoch-Schonlein purpura nephritis (HSPN).</p><p><b>METHODS</b>The 141 HSP children patients with bleeding of the blood stasis syndrome and of the blood heat syndrome (having normal results of urine routines) were assigned to the blood activating and stasis removing group and the blood cooling and arresting group. They were treated with blood activating and stasis removing herbs and blood cooling and arresting herbs respectively for eight weeks. The occurrence rate and time of the renal injury, changes of transforming growth factor (TGF), D-dimer (D-D), immunoglobulin (Ig), urine micro-protein, and urease before and after treatment were observed.</p><p><b>RESULTS</b>The occurrence of the renal injury in the blood activating and stasis removing group was 36.2%, obviously lower than that in the blood cooling and arresting group (69.4%). The occurrence time of the renal injury was 32.2 +/- 10.6 days, obviously later than that in the blood cooling and arresting group (20.0 +/- 9.0 days), showing statistical difference (P<0.05). The levels of TGF, D-D, IgA, microglobulin (MG), immunoglobulin G (IgG), albuminuria (ALB) of children patients in the blood activating and stasis removing group were lower after treatment than before treatment, showing significant difference (P<0.05). Significant difference was also shown when compared with those of the blood cooling and arresting group (P<0.05).</p><p><b>CONCLUSION</b>The application of activating blood and removing stasis method could lower the probability of the renal injury in Henoch-Schonlein purpura (HSP). It played a role in preventing the occurrence of HSPN.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Vasculitis por IgA
/
Medicamentos Herbarios Chinos
/
Epidemiología
/
Incidencia
/
Usos Terapéuticos
/
Quimioterapia
/
Enfermedades Renales
/
Fitoterapia
Tipo de estudio:
Estudio de incidencia
/
Estudio pronóstico
Límite:
Niño
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Chinese Journal of Integrated Traditional and Western Medicine
Año:
2011
Tipo del documento:
Artículo
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