Relations between nonalcoholic fatty liver disease and metabolic syndrome / 中华流行病学杂志

ABSTRACT

Objective To analyze the relation between nonalcoholic fatty liver disease (NAFLD) and metabolic syndrome (MS) among adults from the Functional University Society (FUS).Methods This survey was conducted among the staff of Wuhan University who underwent physical check-ups from 2010 to 2011 at the Affiliated Hospital of Wuhan University.The participants had records related to medical history,clinical examination,anthropometry,laboratory tests and routine liver ultrasonography.According to the diagnostic criteria of NAFLD,the cases were divided into two groups—with NAFLD or without.MS and its relevant risk factors of the two groups were compared.Results 1) The prevalence rates of nonalcoholic fatty liver disease and MS were 20.7％,and 13.3％,respectively.People with nonalcoholic fatty liver disease had higher levels of BMI,SBP,DBP,TG,FPG and lower level of HDL-C than those who did not have the problem.2) The risks of NAFLD group in developing MS,obesity,hypertension and dyslipidemia were higher than the non-group (P＜0.001).3) The NAFLD group had 1.66,4.22,8.72 and 25.62 times chances of having 1 to 4 risk factors on MS than those without NAFLD.Conclusion NAFLD was closely associated with MS and its relevant risk factors.