Batch and fed-batch production of butyric acid by clostridium butyricum ZJUCB / 浙江大学学报(英文版)(B辑:生物医学和生物技术)
Journal of Zhejiang University. Science. B
;
(12): 1076-1080, 2005.
Artículo
en Inglés
| WPRIM
| ID: wpr-263258
ABSTRACT
The production of butyric acid by Clostridium butyricum ZJUCB at various pH values was investigated. In order to study the effect of pH on cell growth, butyric acid biosynthesis and reducing sugar consumption, different cultivation pH values ranging from 6.0 to 7.5 were evaluated in 5-L bioreactor. In controlled pH batch fermentation, the optimum pH for cell growth and butyric acid production was 6.5 with a cell yield of 3.65 g/L and butyric acid yield of 12.25 g/L. Based on these results, this study then compared batch and fed-batch fermentation of butyric acid production at pH 6.5. Maximum value (16.74 g/L) of butyric acid concentration was obtained in fed-batch fermentation compared to 12.25 g/L in batch fermentation. It was concluded that cultivation under fed-batch fermentation mode could enhance butyric acid production significantly (P<0.01) by C. butyricum ZJUCB.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Técnicas de Cultivo de Célula
/
Reactores Biológicos
/
Ácido Butírico
/
Clostridium butyricum
/
Proliferación Celular
/
Glucosa
/
Concentración de Iones de Hidrógeno
/
Metabolismo
/
Métodos
/
Microbiología
Idioma:
Inglés
Revista:
Journal of Zhejiang University. Science. B
Año:
2005
Tipo del documento:
Artículo
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