Polymorphism of CYP1A1 gene Msp I site in the Mongolian and Han nationality populations of Inner Mongolia of China / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 333-334, 2006.
Artículo
en Chino
| WPRIM
| ID: wpr-263782
ABSTRACT
<p><b>OBJECTIVE</b>To study the polymorphism of CYP1A1 gene Msp I site in the Mongolian and Han nationality populations of Inner Mongolia.</p><p><b>METHODS</b>The PCR-restriction fragment length polymorphism(PCR-RFLP) technique was used to analyze the genotypes of CYP1A1 gene Msp I site in 80 subjects of Mongolian nationality and 120 subjects of Han nationality among whom there is no blood relationship each other.</p><p><b>RESULTS</b>The genotype frequency of CYP1A1 gene Msp I site showed that the wild-type, heterozygote, homozygous variants were 35.0%, 48.7%, 16.3% and 33.3%, 52.5%, 14.2% respectively distributions of Mongolian nationality and Han nationality population, and the Chi-square tests showed that there was no significant difference between the two groups.</p><p><b>CONCLUSION</b>The genotype frequency distributions of CYP1A1 gene Msp I site did not exhibit the obvious difference between Mongolian nationality and Han nationality population of Inner Mongolia.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Polimorfismo Genético
/
Sitios de Unión
/
Polimorfismo de Longitud del Fragmento de Restricción
/
China
/
Reacción en Cadena de la Polimerasa
/
Desoxirribonucleasa HpaII
/
Citocromo P-450 CYP1A1
/
Etnología
/
Frecuencia de los Genes
/
Genética
Límite:
Adolescente
/
Adulto
/
Anciano
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
Asia
Idioma:
Chino
Revista:
Chinese Journal of Medical Genetics
Año:
2006
Tipo del documento:
Artículo
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