Analysis of HLA-DRB1 allele polymorphism in the Fujian Han nationality population of China / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 240-241, 2006.
Artículo
en Chino
| WPRIM
| ID: wpr-263805
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the HLA-DRB1 allele polymorphism in Fujian Han nationality population.</p><p><b>METHODS</b>Six hundred and twenty individual samples collected from unrelated Fujian Han population were subjected to genotyping using oligonucleotide microarray technique. And the allele frequencies of HLA-DRB1 were calculated and compared with other populations.</p><p><b>RESULTS</b>Fourteen HLA-DRB1 alleles of Fujian Han population were detected. The gene frequencies ordered from high to low were HLA-DRB1*9, 12, 15, 4, 8 respectively.</p><p><b>CONCLUSION</b>The HLA-DRB1 distribution of Fujian Han population shares some genetic characters with southern Chinese Han populations, but these characters differ from northern Chinese populations.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Polimorfismo Genético
/
Etnicidad
/
Antígenos HLA-DR
/
China
/
Grupos de Población
/
Pueblo Asiatico
/
Alelos
/
Etnología
/
Cadenas HLA-DRB1
/
Frecuencia de los Genes
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Chino
Revista:
Chinese Journal of Medical Genetics
Año:
2006
Tipo del documento:
Artículo
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