The prognostic value of human neuroendocrine clone on colorectal carcinoma / 中华外科杂志
Chinese Journal of Surgery
;
(12): 706-709, 2005.
Artículo
en Chino
| WPRIM
| ID: wpr-264440
ABSTRACT
<p><b>OBJECTIVE</b>To demonstrate the prognostic value of neuroendocrine clone on colorectal carcinoma.</p><p><b>METHODS</b>The immunochemistry methods were used to investigate the percent of neuroendocrine carcinoma in 73 human colorectal carcinoma. Retrospective analysis and follow-up were carried out in all patients.</p><p><b>RESULTS</b>In all 73 cases of colorectal carcinoma, the total percentage of neuroendocrine carcinoma was 17.8%. Neuroendocrine carcinoma included 11 synapse positive, 6 chromogranin positive and 4 both positive. The major factors related to the prevalence of neuroendocrine carcinoma were sex, age, tumor location and Dukes' stage. And the 1-year survival rate of the patients who suffered from neuroendocrine carcinoma is obviously lower than that of other colorectal carcinoma.</p><p><b>CONCLUSIONS</b>The neuroendocrine carcinoma is a special kind of human colorectal carcinoma, and neuroendocrine clone may be a new marker of the malignant potency. The neuroendocrine clone has its prognostic value and may be a novel therapeutic target.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Pronóstico
/
Neoplasias Colorrectales
/
Tasa de Supervivencia
/
Estudios Retrospectivos
/
Mortalidad
/
Cromograninas
/
Sinapsinas
/
Carcinoma Neuroendocrino
/
Metabolismo
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Límite:
Adulto
/
Anciano
/
Aged80
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Chinese Journal of Surgery
Año:
2005
Tipo del documento:
Artículo
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