Rapid Identification of Legionella Pathogenicity by Surface-Enhanced Raman Spectroscopy / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
;
(12): 437-444, 2015.
Artículo
en Inglés
| WPRIM
| ID: wpr-264565
ABSTRACT
<p><b>OBJECTIVE</b>To establish Surface-enhanced Raman Spectroscopy (SERS) can be used as a rapid and reliable method to distinguish virulent strain and mild strain of L. pneumophila.</p><p><b>METHODS</b>Mortality data were collected from company departments through administrative documents, death certificates, etc. Trend analyses of cancer mortality were performed on the basis of 925 cancer deaths between 2001 and 2010.</p><p><b>RESULTS</b>Our results indicated that the peaks of high virulence strains reached ⋝4000. This criterion was verified by subsequent cell experiments. In addition, we also conducted SERS rapid identification on the virulence of several collected clinical strains and obtained accurate results.</p><p><b>CONCLUSION</b>The present study indicates that the established SERS protocol can be used as a rapid and reliable method to distinguish virulent and mildly virulent strains of L. pneumophila, which can be further used in clinical samples.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Espectrometría Raman
/
Factores de Tiempo
/
Virulencia
/
Legionella
/
Línea Celular
/
Química
/
Ácido Cítrico
/
Nanopartículas
/
Oro
/
Tiopronina
Tipo de estudio:
Guía de Práctica Clínica
/
Estudio pronóstico
Límite:
Humanos
Idioma:
Inglés
Revista:
Biomedical and Environmental Sciences
Año:
2015
Tipo del documento:
Artículo
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