Studies on flavonoids and amides from herbs of Solanum lyratum / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the chemical constituents in 95% alcohol extract of Solanum lyratum.</p><p><b>METHOD</b>The compounds were isolated by column chromatography over silica gel, and purified by Sephadex LH-20 column chromatography and preparative TLC. The structures were elucidated on the basis of physicochemical properties and spectral data.</p><p><b>RESULT</b>Eleven compounds were isolated and identified as formononetin (1), vanillic acid (2), genistein (3), apigenin (4), N-trans-feruloyltyramine (5), N-p-coumaroyltyramine (6), daidzein (7), caffeic aicd (8), protocatechuic acid (9), daidzin (10), and N-trans-feruloyl-3-methyldopamine (11).</p><p><b>CONCLUSION</b>For the first time, compound 11 was separated from Solanaceae plant, and compounds 5 and 10 were isolated from Solanum, and compounds 1, 3, 4, 7 and 9 were obtained from this plant for the first time.</p>